Picamilon vs Phenibut, and the Benefits, Side Effects and Doses of Each Drug

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Picamilon vs Phenibut, and the Benefits, Side Effects and Doses of Each Drug

Picamilon vs Phenibut, and the Benefits, Side Effects and Doses of Each Over the Long-Term

Picamilon is a mood enhancer, anxiety pill, and smart drug that is helping people around the world integrate themselves back into society from isolated lives and increasing mental clarity to help aid in work and other projects in which they may engage. Sold as a nutritional supplement, it is quickly becoming known as a “wonder drug” for many who suffer from anxiety, post-traumatic stress disorder and many other things. The following article will look into Picamilon vs Phenibut, and will strive to compare each potent nootropic drug in as great a detail as possible, taking into account all of the amazing benefits, risks, rewards, side effects and downsides of each drug. For more information on this and similar drug topics, subscribe to our blog for a free sample of nootropics worth over fifty dollars, and comment with your questions.

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What is Picamilon, and How Does the Debate of Picamilon vs Phenibut Fare?

Developed in Russia in 1969, Picamilon, also known as N-nicotinoyl-GABA, is a drug that is formed by a synthetic combination of niacin and gamma-aminobutryic acid or GABA. GABA is one of the inhibitory transmitters in the brain. It off-sets excessive activity of neurons in the brain that can lead to anxiety, stress and fixations on negative thoughts. Picamilon is a substitute for this. Niacin and GABA have been bonded together in order to restore levels of the GABA neurotransmitter for people who struggle with mood disorders. It enhances mood, helps with sleep, relaxation, and stimulates the GABA receptors in the brain, making it easier to think and make decisions.

With regards to Phenibut on the matter, it is actually significantly stronger than Picamilon with regards to its mood boosting effects, effects as a sleep aid, and in its ability to make the user drunk and euphoric. So when online, people choose to debate Picamilon vs Phenibut in online websites, blogs or forums, just know that while they are very similar, Phenibut is far superior in the strength of its effects, however Picamilon may be better for regular use in that it is much weaker and has a much less addictive potential, though cautions should definitely still be taken while using either drug.

What is the Proper Dosage of Picamilon vs Phenibut?

Appropriate dosages for Picamilon range from 50 mg to 300 mg per day. It is generally viewed as a very safe drug. But it should only be taken under a doctor’s supervision. Anytime a person takes a supplement it will influence how the brain works and extra caution has to be taken to prevent possible side effects. People generally are unlikely to have any problems while taking Picamilon if it is taken in the appropriate dosage of less than 500 mg each day. It is also not known to cause problems that are related to addiction abuse or tolerance withdrawals.

Compared to this, Phenibut has a slightly stronger dosage, and higher dosage as well, in that the typical dosage of Picamilon is typically going to range from 500 to 1500 milligrams at a time. When comparing the dosages of Picamilon and Phenibut against one another, just be sure to always keep in mind not to dose too high, and to use the minimum effective dosage whenever possible in order to avoid excess side effects and other problems.

What Side Effects Will Be Experienced? Comparing the Side Effects of Picamilon vs Phenibut

There are both positive and negative side effects to taking Picamilon, and the same is absolutely true for Phenibut, the following lists will work for both drugs. Positive effects are that Picamilon and Phenibut both help to:


  • Regulate blood pressure
  • Alleviate migraines
  • Aid in poor cerebral flow and circulation


Negative side effects are also present, but are usually the result of taking too much of the drug. Negative symptoms of Picamilon and Phenibut can both include:


  • Headaches
  • Nervousness
  • Fatigue
  • Intestinal Issues
  • Drowsiness
  • Low mood if taken too many days in a row


These negative side effects can usually be taken care of by merely reducing the amount of dosage taken.

However, one of the biggest concerns surrounding Picamilon is the fact that it acts as a MAOI (monoamine oxidase inhibitor) which means it inhibits the activities of an enzyme that breaks down monoamines such as dopamine. Picamilon vs NootropicsMAOIs can be very dangerous when taken with other drugs because of the chemical reactions. But Picamilon is not included in the hazardous MAOI drug list.

Long-Term Use of Picamilon vs Phenibut

It is recommended that Picamilon not be taken for very long periods of time. Several users have recommended after using it for a period of time, to use it for two additional months, then discontinue it for two weeks before starting the cycle once more. Clinical trials showed no disturbance in the kidneys or urinary system when taking Picamilon. Long term use of either Picamilon or Phenibut is highly advised against, and when comparing the addiction potential of Picamilon vs Phenibut, both drugs are actually very close in how they can rapidly increase tolerance and become habit forming.

Overall, Picamilon and Phenibut are two very powerful nootropics, and what some nootropic guru’s will do in order to increase their effects to an even greater degree, is stack these supplements with other nootropics, including:









CDP Choline

Alpha GPC Choline

Uridine Monophosphate



DAA or D-Aspatic Acid

Fish Oil

Krill Oil


Rhodiola Rosea 3% Salidroside


and a host of other similar and related nootropics with similar potency and effects and benefits on the user, subscribe for additional details on this matter.

How to Use Picamilon vs Phenibut Over the Long-Term Safely and Effectively to Properly Avoid Addiction and Withdrawal

Picamilon should be used in a stack and cycle method. Meaning it can be combined with another nootropic like Phenibut. Begin with Picamilon and use for three or four days and take two days of the cycle. During these two days, take the other supplement like Phenibut, but do not take them both at the same time as it can actually be very dangerous.

What People Are Saying About Picamilon vs Phenibut and Which Drug is Winning the Debate?

Those who have taken Picamilon say they have experienced mental clarity and energy without the need for stimulants such as coffee or nicotine. Many report their depression diminished or disappeared, while their anxiety was also eliminated in social settings. Waking up well rested, being sick less often and many other positive results. With Phenibut, the effects are very similar, but the verdict is out on these reviews that Phenibut is actually much more powerful than Phenibut. You can read up about further reviews on the subject online at the following .gov and forum review URLS:








Conclusion on the Effects of Picamilon vs Phenibut, and The Verdict on the Picamilon vs Phenibut Debate

Picamilon is a perfect drug for those who experience problems with their moods. But while mood regulation can be attained, there are still risks involved when taking it because of proper dosage administration. With a doctor’s supervision, Picamilon is a great suggestion. But alone, it is not. However, for those who suffer from disorders like PTSD, panic disorder and extreme anxiety disorder, this drug has opened up experiences that were not available to them until now. That makes it very important and worthy to be sold on the market in the United States. Phenibut, overall, looks to be the clear winner in the debate between Picamilon vs Phenibut, and overall, it wins by a very strong margin. Be sure to use both Picamilon and Phenibut very carefully, and not to dose either drug too excessively, as addiction and withdrawal can ensue as a result. For more information on Picamilon, Phenibut, and similar and related Smart Drugs, be sure to subscribe to our blog for a free sample of nootropics worth over fifty dollars, and to comment down below on this blog post with your thoughts and opinions on the article, and we’ll get back to you within one business day with a response! Until next time, you heard it first right here at Nootropics University.com.




  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

By | 2017-09-23T19:10:30+00:00 July 1st, 2017|Nootropics Versus Nootropics, Phenibut, Picamilon|0 Comments

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