How to Increase Acetylcholine

//How to Increase Acetylcholine

How to Increase Acetylcholine With Supplements

Any burgeoning bio-hacker worth their salt knows the value of a quality cholinergic supplement. Acetylcholine is one of the primary neurotransmitters responsible for memory storage and consolidation tasks, which are obviously vital for learning processes. Acetylcholine is also thought to be an important factor in neuroplasticity. Low levels of acetylcholine are a common precursor for a host of age related cognitive issues including Alzheimers and dementia. Maintaining healthy acetylcholine levels is a major part of ensuring your brain’s baseline functioning. How to Increase acetylcholine via Smart Drugs, is going to be the main topic of this article.

Acetylcholine and it’s precursor choline (found in soy, lecithin, fish, eggs and other dietary sources) are vital building blocks for a healthy brain. As a result, maintaining adequate levels of acetylcholine in the synaptic gap will be of primary importance for maintaining healthy baseline functioning and improving from there. The most commonly used choline supplements to jack up the way that choline works in the brain, are racetam nootropics. These include

Piracetam-Piracetam is the original nootropic Smart Drug, and is the baseline that a host of other nootropics are compared to. Helps improve memory, mood, focus and energy.

Aniracetam-5 times more powerful than Piracetam, also has anxiety lowering effects.

Oxiracetam- Oxiracetam is a potent stimulant racetam that is fifteen to twenty times stronger than Piracetam. Also known as the speedy racetam, Oxiracetam can give the user amazing levels of focus and energy, but in a way that is subtle and not overt. Oxiracetam is a powerful nootropic drug with a wide range of cognitive benefits, and for best effects should be used with a common choline source, such as Alpha GPC or CDP Choline.

Pramiracetam- 30 times stronger than Piracetam, more side effects, but the most powerful basic racetam, amazing for mood, memory and focus.

Phenylpiracetam-40x stronger than Piracetam, is a stimulant nootropic that functions mainly on dopamine and acetylcholine.

Noopept- one thousand times stronger than the base Smart Drug, of Piracetam.

Stores where you can buy Supplements to Increase Acetylcholine Long-Term

  1. nootropicsuniversity.com
  2. smartdrugsforcollege.com
  3. Modup.net
  4. modafinil.co.uk
  5. peaknootropics.com

How to Increase Acetylcholine Long-Term

Acetycholine itself is not available in supplement form but, as is the case with 5-HTP and Serotonin, precursors exist that can raise acetylcholine levels as well as cholinergic drugs like the racetams. Brain fog and memory issues may be side effects of low How to Increase Acetylcholinecholine or acetylcholine levels. Choline supplements like choline bitartrate, citicoline or alpha gpc can raise levels of choline, an essential fatty acid and important brain nutrient needed to produce acetylcholine.

Choline citrate and bitartrate have relatively low bio-availability compared to higher quality choline sources like citicoline and gpc. Additionally citicoline and gpc have stand-alone nootropic qualities. Some studies suggest that they may even be comparable to racetams like piracetam or oxiracetam used alone.

How to Increase Acetylcholine with Nootropics

There are three basic classes of acetylcholine supplements you should learn about if you’re interested in implementing a nootropic regimen. The first type are cholinergic drugs like the racetam family that act as agonists. Cholinergic agonists will upmodulate production of the neurotransmitter in the synapse. The second type would be choline sources, the acetylcholine precursors themselves such as the ones mentioned earlier.

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Choline supplements are especially important if you’re using cholinergic agonists since so many people are already deficient in choline. Use of cholinergic activators like the racetams without proper dietary choline or supplementation can result in brain fog or headache.

Finally there are the acetylcholinesterase inhibitors. Acetylcholinesterase is an enzyme that degrades acetylcholine in the synaptic gap. Acetylcholinesterase inhibitors increase acetylcholine levels by lowering the levels of this enzyme allowing the acetylcholine already in the system to remain in the synapse longer.

There are three basic types of Acetylcholine supplements that you can use as nootropics. The first type – acetylcholine agonists – is epitomized by Piracetam and other racetams. These supplements essentially stimulate receptors in your brain that cause more acetylcholine to be released. The second type of supplement includes Choline sources and Acetylcholine intermediates. This second grouping includes Choline Bitartrate, Alpha GPC and CDP Choline – all of which allow for greater production of acetylcholine in the brain. The third family of supplements are Acetylcholinesterase Antagonists. Acetylcholinesterase is a naturally occurring enzyme which causes the breakdown of Acetylcholine.

How to Increase Acetylcholine with Racetams and Choline

By inhibiting its production, you can increase the amount of acetylcholine neurotransmitter present in the brain. Many of the most popular nootropics are acetylcholine agonists or cholinergic supplements. Piracetam, Aniracetam, Pramiracetam, Oxiraetam and Noopept all work this way – stimulating your acetylcholine receptors to release more of the stored neurotransmitter. When you have higher levels of acetylcholine, it is easier for your brain to form new connections between How to Increase Acetylcholine with Nootropic Smart Drug Supplementsneurons, to store new memories and to recall old memories. Higher concentration of acetylcholine in the cerebral cortex has also been shown to increase attention span, focus, neuroplasticity and communication between the left and right hemispheres of your brain.

Final Thoughts on How to Increase Acetylcholine

The five most common choline and acetylcholine supplements include phosphatidylcholine and soy lecithin, choline bitartate or citrate, cdp or citicoline, alpha gpc and the racetam family of supplements. Remember that choline is water soluble so it won’t store up in fat cells and is eliminated readily like the b-vitamins which are closely related chemically speaking.

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

By | 2018-07-07T01:13:33+00:00 February 14th, 2017|Acetylcholine|0 Comments

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