Coluracetam Dosage, Side Effects and Review Logs
This is a nootropic drug that was created by a Japanese company, Mitsubishi Tanabe Company in 2005 from Piracetam. The company later transferred the patent to BrainCells Inc, a US company based in California. BrainCells Inc is known for products that treat infections of the central nervous system (CNS). Coluracetam was initially meant to treat Alzheimer’s disease. However, this never materialized. Currently, the drug is used as an anxiolytic and to treat depressive disorders. Coluracetam dosage reviews usually say that 40mg of the drug is sufficient.
Coluracetam belongs to the Racetams family. It is also known as MKC-231, BCI-540, 2-(2-oxopyrrolidin-1-yl)-N-(2, 3-dimethyl-5, 6, 7, 8-tetrahydrofuro2, 3-b quinolin-4-yl)acetoamide.
Benefits and Effects of a Proper Coluracetam Dosage
Coluracetam is the only high affinity choline uptake (HACU) enhancer. This unique characteristic distinguishes the drug from other nootropics. This feature makes Coluracetam to increase the flow of Acetylcholine in the brain hence enhancing the brain functions of learning, mood, intelligence and memory.
BrainCells Inc reports that Coluracetam can treat different disorders and diseases that affect the central nervous system and the brain such as optic nerve injuries and ischemic retinopathy. Since Coluracetam has the potential to reverse choline production loss, its potential to treat schizophrenia is being considered. These are the principal medical benefits of Coluracetam. It is important to note that research is currently ongoing to reach conclusive findings on these clinical applications of the drug. Coluracetam, unlike other racetams that burn choline, actually helps to create choline in the brain while it uses it. A typical Coluracetam dosage, in this case, would be 10-30 milligrams.
The non-clinical benefits of Coluracetam are mainly due to the fact that is a high affinity choline uptake (HACU) enhancer. The drug is useful in:
l Improving memory
l Enhancing cognition
l Improved decision making
l Improving eyesight.
These Coluracetam benefits arise from increased Acetylcholine synthesis and choline uptake. The drug also reduces cytotoxicity of the brain ( the state where brain cells are toxic to the body cells). Cytotoxicity occurs when oxygen supply to the brain is limited causing an inflow of calcium in cortical neurons.
The drug is also used as an antidepressant to treat different types of depression. Moreover, it can be effective against hangovers and stress. It is therefore considered a smart drug that boosts motivation.
The best Coluracetam Dosage
It is important to note that there is no medically recommended dose when using Coluracetam at the time of writing this post. However, at most 200mg per day is advisable. Moreover, the dosage can vary based on why someone is using the drug. For example, someone taking the nootropic to treat a general anxiety disorder or a main depressive disorder should take 300 mg per day in order to reap maximum benefits. Another factor that affects dosage is where the Coluracetam is bought in the first place. This is because the retailing company can have its own recommended dosage. The sure way to know the right dosage for you is to ask your doctor.
Side effects of a 200 Milligram Coluracetam Dosage
Coluracetam is generally safe to use. Its use has few side effects. It should not be taken by pregnant or breast-feeding women. Some people can also exhibit allergic reactions after using Coluracetam. Regular side effects are headache and nausea which can be countered if the drug is stacked with Alpha GPC, CDP Choline, or Centrophenoxine. Stacking reduces side effects. When you buy the nootropic, you can request for information from the seller on the best stacking combination. At 200mg, side effects can include jitters, tiredness, and headache.
How to use Coluracetam at a Proper Dosage
Most people take the drug sublingually, that is in form of a solution whose drops are placed under the tongue using a pipette dropper. This method provides quicker absorption and prevents first pass metabolism in the intestines.
Coluracetam is mainly sold as a powder. However, some companies offer it as a liquid base thereby making it very easy to take sublingually.
Stacking is always recommended. Stacking maximizes the Coluracetam potential, yields more positive results and minimizes or eradicates side effects. Coluracetam is stacked with Choline from soruces such as Alpha GPC, Citicholine, and Centrophenoxine, among others. Coluracetam can also be stacked with other powerful nootrpics such as Noopept.
Because Coluracetam is soluble in fat, it should be taken with a meal that contains healthy fats. If this is not possible, a tablespoon olive oil, cold-pressed coconut oil or extra virgin oil can be used to ensure faster absorption.
Coluracetam has not been round for many years. It was first produced in 2005 by Mitsubishi Tanabe in Japan. There is therefore lesser research than the other traditional nootropics. However, since BrainCells Inc got the patent for the drug, they have been carrying out research on the drug. The research findings are promising so far.
What does Coluracetam do at a 100 milligram Coluracetam Dosage
Coluracetam, just like most of the other Racetam compounds increases the uptake of choline. Coluracetam does this by interacting with the high affinity choline uptake (HACU) process that is responsible for choline absorption into neurons. The increase in the uptake of choline takes place during acetylcholine synthesis. Coluracetam improves the preservation of choline during the process thereby increasing alertness, memory and attention.
Coluracetam has also been shown to improve AMPA potentiation, a process that triggers alertness and cognitive function.
Coluracetam vs Adderall
l Aderall was first produced in 1970 while Coluracetam has been around since 20005
l Both are strong nootropics
Coluracetam vs Piracetam
l Piracetam was developed in 1964; while Coluracetam was developed in 2005.
l Both Coluracetam and Piracetam are recommended for Alzheimer’s and age-related memory loss
l Coluracetam has a half-life of 3.5 hours while Piracetam has a half-life of 5 hours
l The suggested dose for Piracetam is higher than Coluracetam.
Coluracetam vs Aniracetam
l Aniracetam was developed in the 1970s while Coluracetam entered the fray in 2005.
l Aniracetam has a shorter half-life (1-2) hours than Coluracetam (3.5hrs)
l The typical dosage for Aniracetam is 750mg per day while for Coluracetam, it should not exceed 300 mg.
l Both Coluracetam and Aniracetam have ampakine activity.
Coluracetam vs Oxiracetam
l Oxiracetam is soluble in water and was first reported in 1977
l Both belong compounds are derived from Piracetam.
l Oxiracetam has a longer half-life (8hrs) than Coluracetam.
l Typical dose for Oxiracetam is higher at 750mg taken twice a day.
Coluracetam vs Pramiracetam
l Pramiracetam has a longer history of use than Coluracetam
l Both have a very similar mode of action- improving the efficiency of high affinity choline uptake (HACU)
While Coluracetam is a newer creation in the Racetam family, its use has not been associated with any serious complication. It does not pose dangers to users. However, since it was recently created and the fact that there is not much research available on the compound, its use must be under the direction of a doctor. If used at as recommended, there is no cause for alarm over negative effects.
Coluracetam legal status
Coluraceteam’s legality either as research chemical or a compound for human consumption varies from one country to another. It is always important to check this fact before buying Coluracetam.
Final Thoughts on Coluracetam Dosage Reviews
Coluracetam, a member of the Racetam drugs is a new nootropic that has promising results. BrainCells Inc, the company that got the patent from the Japan company Mitsubishi Tanabe Pharma Corporation that first developed the drug is still conducting research on the usefulness of this compound. It has shown helpful non-clinical benefits such improved memory, increased alertness, better eyesight and improved decision making. The best Coluracetam dosage from the looks of it is around 200 milligrams daily.
*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement